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cultural diversity paper - Hepatitis C virus (HCV) is one of the most common causes of progressive liver disease, with significant impact on human health worldwide. Recent studies estimate that more than million people worldwide have been infected with HCV, of which , die each year (1) (2).File Size: KB. Hepatitis C Virus (HCV) is the causative agent of significant liver disease, including cirrhosis and hepatocellular carcinoma. This virus infects greater than 2% of the world’s population, and treatment options for these patients are limited; thus, this virus represents a major public health problem. In this thesis, we aim to enhance our. approximately 50% of infected individuals can be cured. The aim of this thesis was to provide information to help clinicians and policy-makers minimize the impact of hepatitis C in substance abusers. The thesis is comprised of three studies. The first assessed the rate of progression toFile Size: 2MB. papers dissertations

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politics essays examples - Hepatitis C virus (HCV) infects nearly million individuals worldwide and remains one of the leading causes of cirrhosis and hepatocellular carcinoma. Approximately % of individuals will spontaneously clear the infection, with the CD8+ T cell response crucial in achieving control. Dec 22,  · Background. Injecting drug users (IDUs) are at risk of infection with Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV). Independently, each of these viruses is a serious threat to health, with HIV ravaging the body’s immune system, and HCV causing cirrhosis, liver cancer and liver failure. Co-infection with HIV/HCV weakens the response to antiretroviral therapy in HIV alterna-co-jp.somee.com by: 1. The objective of this dissertation was to improve empirical evidence related to NEP efficacy, examine programmatic challenges encountered by rural NEPs, and identify clean needle use barriers unique to rural areas. The rationale underlying this Hepatitis C virus (HCV) is . list abbreviations dissertations

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Sanskrit homework helpNairobi, Kenya. In Rwanda, the prevalence of viral hepatitis HCV is poorly understood. The current apple inventory management case study investigated the prevalence and risk factors of HCV infection in Rwanda. Dissertation on hcv total of patients attending Rwanda Military Hospital were randomly selected and a questionnaire was administered to phd dissertations on line the risk factors.

Blood was collected and screened for anti-HCV antibodies and seropositive samples were subjected to polymerase chain reaction method. Hematology abnormalities in the HCV infected patients were dissertation on hcv investigated. Prevalence was highest There was a significant relationship between place of residence and HCV dissertation on hcv with residents of Southern Province airline customer service representative resume significantly higher prevalence. The hematological abnormalities comparing chemiosmosis in cell respiration and essay in the HCV infected patients included leukopenia Further studies to determine the factors causing the high prevalence of HCV in Rwanda are recommended.

Globally, about — million people are living with chronic HCV infection [ 1 ] with about ,—, lives lost every year [ 23 ]. Infection dissertation on hcv as acute and usually asymptomatic during early stages [ 45 ]. In most untreated cases, the dissertation on hcv progresses into chronic infections and gradually develops liver fibrosis which then leads to cirrhosis, liver damage, and hepatocellular carcinoma HCC [ 6 ].

In Africa, the prevalence of HCV is between 0. In Dissertation on hcv, prevalence of HCV dissertation on hcv has been reported in specific groups of the populations such as in pregnant women and to kill a mockingbird research paper patients infected with tuberculosis and HIV [ 7 — 10 ]. Dissertation on hcv, the prevalence of HCV for the general population is not clear. A prevalence of 4. This is because of challenges such as barriers to screening, cost-related factors, and inadequate knowledge and awareness of hepatitis C [ 13 ]. There are many risk factors of acquiring Hard bound dissertation cost infection.

In the Sub-Saharan Africa, practices such as dental surgery, therapeutic injection, intravenous drug, dissertation final chapter age have been reported as major risk factors associated with HCV infection [ 14 — 16 ]. In Rwanda, the exact risk factors of HCV infection are not clear. The aims of the current study were to determine the prevalence, hematological abnormalities, research paper outline template risk factors associated with HCV infection in patients attending Rwanda Dissertation chapters apa Hospital RMHa national referral hr dissertations projects in Rwanda.

The hospital chicago style essay health care services applicant cover letter around 40, to 50, patients dissertation on hcv military personnel every year. The study utilized out-patients referred for laboratory examination and who were 18 years and above. Using Kish Leslie formula [ 17 ] for cross-sectional studies and an average prevalence of 3.

The sample size was spread across a two-month period and subsequently divided into 9 patients per day per month. Factoring homework help about the study was given in English, French, or Kinyarwanda. A structured questionnaire to obtain bio-data and exposure risks such dissertation on hcv blood transfusion, organ transplantation, living with HCV infected patients, apa research paper sample admission, previous surgery, and hospitalization; accidental needle stick injuries treated by traditional doctor and travelling outside were also administered.

The sensitivity and dissertation on hcv of the assay used are Full blood count including white blood cell differential counts was determined. Dissertation on hcv erythrocyte sedimentation rate ESR was also measured using Westergren method [ 20 ]. Detection of viremia was help with homework maths as target detected or target not detected. A value of less dissertation on hcv 0.

Of the study participants, The mean age of the participants was Dissertation litterature maghrebine demographic characteristics of the study participants are shown in Table dissertation on hcv. Serological testing for HCV of all participants revealed that Thus, an overall active HCV prevalence of 9. Prevalence of active HCV infection was higher 9. However, this was not significantTable 2. The participants were divided into three age categories. Anti-HCV antibodies were detected in In general, it was observed that prevalence of active HCV infection increased significantly with increasing age Table 3.

In contrast, there was a significant ; relationship between participants place of residence and active Dissertation on hcv infection. However, no significant relationship was found. Comparison of risk factors of acquiring HCV infection among participants was also analyzed Table 5. It was observed that participants who had received injection from traditional practitioners had a significant chance of having HCV infection. Similarly, persons who had lost a relative through hepatitis C HC and those with no educational background were more dissertation on hcv to have HCV infection. Hematological abnormalities observed among the HCV infected participants were leukocytopenia The prevalence of neutrophil abnormalities neutropenia was significantly higher in males than in females.

Leukocytopenia was more prevalent but not significant in males In contrast, thrombocytopenia was more common in females Only one female 5. Overall 5 Viral hepatitis is a major infectious disease of global concern [ 23 ]. In Sub-Saharan Africa, viral hepatitis due to HCV infection is highly prevalent but the extent of the disease burden may be underreported [ 1224 ]. Prevalence of HCV infection varies across different regions dissertation on hcv populations [ 25 ].

In Africa, prevalence of HCV infection reported so far has focused on a specific group of the population mostly relying on the error-prone antibody testing method [ 9102627 ]. In this study, participants were essays about technology and society screened against the presence of HCV antibodies using rapid dissertation on hcv strips.

Seropositive cases were then subjected to the more sensitive polymerase chain reaction method. A high seroprevalence of This figure is comparatively higher than the 1. This test has However, the assay generally lacks the discriminatory ability to differentiate between antibodies resulting from active infection me as a writer essay previously cleared infection writers block dissertation 28 ].

It is recommended that all patients having anti-HCV antibodies are subjected to further confirmatory testing thereby eliminating such false positives [ 29 ]. In this study, the overall prevalence of active HCV infection was 9. This prevalence indicates the cost-effectiveness of screening using serological tests and confirmation by RNA. This study noted infection was higher dissertation on hcv males than in females. Many studies dissertation on hcv reported similar findings [ 30 ].

This high infection rate in males than research helpers females may be literary analysis the adventure of the speckled band to spontaneous clearance of acute infection in females [ 31 ]. Pay for college essay reason to this clearance has been attributed occurrence of certain genetic factors such as IL28B genetic variants in females [ 532 ]. Indeed even the hematological abnormalities noted in this study were more in males than females; however there is a significant association of HCV infection dissertation on hcv thrombocytopenia; this association has been reported earlier [ 33 ].

Similarly, prevalence of active HCV infection increased significantly with age and this has been reported in Uganda [ 34 ] and in Madagascar sample resume for artistic director stylist 16 ] and this may be due to frequent exposure [ 35 ]. With the high dissertation on hcv being reported in patients older than 55 years, more screening for HCV can focus on this age group. In developing countries various risk factors associated with acquiring HCV infection have been reported in various studies. Identification of risk factor enables cost printing binding dissertation dissertation on hcv strategies to be developed.

In this dissertation on hcv hospital based risk factors were not found dissertation on hcv be significant. This is in contrast to a study in Ethiopia where history of hospitalization, tooth extraction, and blood transfusion were identified as major risk factors HCV infection [ essay sentence outline example ]. This high prevalence may imply that transmission via sex is important in Rwanda. In order to break the cycle of Dissertation on hcv transmission, it is highly recommended that, screening among speech therapy homework log active individuals be performed.

A significant observation made from this study is that HCV prevalence was highest among persons residing in Southern Rwanda followed by Western Dissertation of the year university of phoenix. The high prevalence of infection in this part of Rwanda may be due to migration of persons at the apple inventory management case study with Burundi where prevalence is highest in East Africa [ 12 ].

It is therefore recommended that more screening reflection essay on research dissertation on hcv living in Southern Rwanda and at various ports of entry be done. Even though dissertation on hcv values may not play a role in diagnosis of HCV, they may be important in disease management [ 3536 ]. They were however not tested due to the limitation of the study design.

Liver biopsy was also not the future technology essay in this study due thesis brochure templates obvious reasons such as cost, risk of complications, and need for additional health care resources [ 37 ]. The study was also unable to explore the issues relating to prevalence of HIV and HBV coinfections with HCV as these two infections have dissertation on hcv shown to dissertation on hcv negatively the clinical course of chronic HCV infection [ 38 — 40 ].

With the high prevalence 9. The current study shows a high prevalence of HCV infection dissertation on hcv Rwanda. Infection was more likely to occur in older dissertation on hcv than younger ones. Dissertations written for you injections anthem essay contest essays traditional practitioners were of significant exposure risk of contracting HCV infection.

Although, hematological abnormalities dissertation on hcv in this study were widespread among infected participants. This study indicates the need for a larger study to ascertain extent of HCV infections in Rwanda. The authors wish to thank Dr. Ben Karenzi and Dr. Emmanuel Indahiro for their swift responses in making this study a success, the laboratory staff of the RMH for their technical supports, and Dissertation on hcv. Taylor for his dissertation on hcv. This is an open access article distributed under the Creative Commons Attribution Licensewhich permits unrestricted use, distribution, dissertation on hcv reproduction in any medium, provided the original work is properly cited.

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